USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: Q96IG0 USC-OGP 2-DE database:  Q96IG0 Q96IG0 General information about the entry View entry in simple text format Entry name LASP1_HUMAN Primary accession number Q96IG0 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=LIM and SH3 domain protein 1; Short=LASP-1; AltName: Full=Metastatic lymph node gene 50 protein; Short=MLN 50;. Gene name Name=LASP1 Synonyms=MLN50 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0456: pI=6.39; Mw=34565 Cross-references UniProtKB/Swiss-Prot Q14847; LASP1_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name LASP1_HUMAN Primary accession number Q14847 Secondary accession number(s) B4DGQ0 Q96ED2 Q96IG0 Sequence was last modified on  January 1, 1998 (version 2) Annotations were last modified on  March 15, 2017 (version 169) Name and origin of the protein Description RecName: Full=LIM and SH3 domain protein 1; Short=LASP-1; AltName: Full=Metastatic lymph node gene 50 protein; Short=MLN 50; Gene name Name=LASP1 Synonyms=MLN50 Encoded on Name=LASP1; Synonyms=MLN50 Keywords 3D-structure; Acetylation; Actin-binding; Alternative splicing; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Ion transport; LIM domain; Metal-binding; Methylation; Phosphoprotein; Reference proteome; Repeat; SH3 domain; Transport; Zinc. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X82456; CAA57833.1; -; mRNA EMBL AK294704; BAG57861.1; -; mRNA EMBL AC006441; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL AC110749; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL BC007560; AAH07560.1; -; mRNA EMBL BC012460; AAH12460.1; -; mRNA CCDS CCDS11331.1; -. [Q14847-1]; . CCDS CCDS62164.1; -. [Q14847-3]; . PIR S68234; S68234; . RefSeq NP_001258537.1; NM_001271608.1. [Q14847-3]; . RefSeq NP_006139.1; NM_006148.3. [Q14847-1]; . UniGene Hs.741156; -; . PDB 3I35; X-ray; 1.40 A; A=202-261 PDBsum 3I35; -; . ProteinModelPortal Q14847; -; . SMR Q14847; -; . BioGrid 110120; 65; . IntAct Q14847; 113; . MINT MINT-5001286; -; . STRING 9606.ENSP00000325240; -; . iPTMnet Q14847; -; . PhosphoSitePlus Q14847; -; . SwissPalm Q14847; -; . DMDM 3122342; -; . OGP Q14847; -; . SWISS-2DPAGE Q14847; -; . EPD Q14847; -; . MaxQB Q14847; -; . PaxDb Q14847; -; . PeptideAtlas Q14847; -; . PRIDE Q14847; -; . DNASU 3927; -; . Ensembl ENST00000318008; ENSP00000325240; ENSG00000002834. [Q14847-1]; . Ensembl ENST00000433206; ENSP00000401048; ENSG00000002834. [Q14847-3]; . Ensembl ENST00000435347; ENSP00000392853; ENSG00000002834. [Q14847-1]; . GeneID 3927; -; . KEGG hsa:3927; -; . UCSC uc002hra.3; human. [Q14847-1]; . CTD 3927; -; . DisGeNET 3927; -; . GeneCards LASP1; -; . HGNC HGNC:6513; LASP1; . HPA CAB022049; -; . HPA HPA012072; -; . MIM 602920; gene; . neXtProt NX_Q14847; -; . OpenTargets ENSG00000002834; -; . PharmGKB PA30298; -; . eggNOG KOG1702; Eukaryota; . eggNOG ENOG4111GQ8; LUCA; . GeneTree ENSGT00530000062924; -; . HOGENOM HOG000006616; -; . HOVERGEN HBG054636; -; . InParanoid Q14847; -; . OMA YGYKEPA; -; . OrthoDB EOG091G0U2O; -; . PhylomeDB Q14847; -; . TreeFam TF319104; -; . SIGNOR Q14847; -; . ChiTaRS LASP1; human; . EvolutionaryTrace Q14847; -; . GeneWiki LASP1; -; . GenomeRNAi 3927; -; . PRO PR:Q14847; -; . Proteomes UP000005640; Chromosome 17; . Bgee ENSG00000002834; -; . CleanEx HS_LASP1; -; . ExpressionAtlas Q14847; baseline and differential; . Genevisible Q14847; HS; . GO GO:0030864; C:cortical actin cytoskeleton; ISS:UniProtKB; . GO GO:0005737; C:cytoplasm; IDA:BHF-UCL; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005925; C:focal adhesion; IDA:UniProtKB; . GO GO:0045296; F:cadherin binding; IDA:BHF-UCL; . GO GO:0015075; F:ion transmembrane transporter activity; ISS:UniProtKB; . GO GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc; . GO GO:0008270; F:zinc ion binding; IEA:InterPro; . GO GO:0006811; P:ion transport; ISS:UniProtKB; . Gene3D 2.10.110.10; -; 1; . InterPro IPR000900; Nebulin_repeat; . InterPro IPR001452; SH3_domain; . InterPro IPR001781; Znf_LIM; . Pfam PF00412; LIM; 1; . Pfam PF00880; Nebulin; 2; . Pfam PF14604; SH3_9; 1; . PRINTS PR00452; SH3DOMAIN; . SMART SM00132; LIM; 1; . SMART SM00227; NEBU; 2; . SMART SM00326; SH3; 1; . SUPFAM SSF50044; SSF50044; 1; . PROSITE PS00478; LIM_DOMAIN_1; 1; . PROSITE PS50023; LIM_DOMAIN_2; 1; . PROSITE PS51216; NEBULIN; 2; . PROSITE PS50002; SH3; 1; .

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